What is the indication of ethambutol?
Ethambutol is indicated in combination with other anti-tuberculosis drugs in the treatment of pulmonary tuberculosis. It has a long duration of action as it is administered daily, and a moderate therapeutic window. Patients should be counselled regarding the risk of optic neuritis and hepatic toxicity.
When is ethambutol contraindicated?
Ethambutol is contraindicated in patients who are known to be hypersensitive to this drug, in patients with known optic neuritis, in patients who are unable to appreciate and report visual side effects or changes in vision (e.g., young children, unconscious patients.
Is ethambutol a broad spectrum antibiotic?
Ethambutol has a broader spectrum of activity against mycobacterial species than isoniazid or rifampin and is therefore used largely in patients with suspected resistance or in atypical mycobacterial infections.
How does ethambutol work in the body?
Ethambutol is an antibiotic and works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.
What is the adverse effect of ethambutol?
SIDE EFFECTS: Headache, loss of appetite, upset stomach, or nausea/vomiting may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.
Can ethambutol be used to treat Mycobacterium tuberculosis?
Background: In recent years, very few effective drugs against Mycobacterium tuberculosis have emerged, which motivates the research with drugs already used in the treatment of tuberculosis. Ethambutol is a bacteriostatic drug that affects cell wall integrity, but the effects of this drug on bacilli are not fully exploited.
What are the side effects of ethambutol?
Ethambutol side effects. severe skin reaction–fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
What is ethambutol used for?
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. 13 Ethambutol was first described in the literature in 1961. 11 It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. 11
What is the effect of carboplatin on ethambutol levels?
Carbidopa may decrease the excretion rate of Ethambutol which could result in a higher serum level. Carboplatin may decrease the excretion rate of Ethambutol which could result in a higher serum level.