What are the organic and inorganic components of bone matrix?
Bone matrix (also known as osteoid) consists of about 33% organic matter (mostly Type I collagen) and 67% inorganic matter (calcium phosphate, mostly hydroxyapatite crystals).
Do osteocytes secrete organic matrix?
Osteoprogenitor cells are the ‘stem’ cells of bone, and are the source of new osteoblasts. Osteoblasts, lining the surface of bone, secrete collagen and the organic matrix of bone (osteoid), which becomes calcified soon after it has been deposited. As they become trapped in the organic matrix, they become osteocytes.
What makes up the organic and inorganic portions of the extracellular matrix?
The main inorganic components of the ECM are calcium-deficient apatite and trace elements. By contrast, the organic ECM is significantly more complex consists mainly of collagen type I (90%), and noncollagenous proteins (10%).
What is the inorganic component of bone matrix?
COMPOSITION OF BONE The inorganic component is primarily crystalline hydroxyapatite: [Ca3(PO4)2]3Ca(OH)2. The organic component of bone comprises more than 30 proteins with type I collagen being the most abundant (>90%) [1,2,12].
What is the inorganic portion of the bone matrix?
calcium hydroxyapatite
The inorganic matrix of bone consists of a calcium hydroxyapatite, which is in a crystalline structure.
What are the inorganic components of bone?
Inorganic Components: – They are mineral salts, mainly Hydroxyapatite (a cristallized form of tricalcium phosphate), some calcium carbonate, and small amount of magnesium hydroxide, fluoride and sulfate.
What is the organic matrix of bone?
Collagen is the principal organic matrix in bone. The triple helical region of the molecule is 1014 amino acids long. In fibrils these molecules are staggered axially by integers of 234 residues or 68 nm (D).
What is the inorganic matrix of bone?
The inorganic matrix of bone consists of a calcium hydroxyapatite, which is in a crystalline structure.
What is the organic matrix?
When the inorganic portion of a bone is dissolved with acid, there remains a model of the bone in a coherent elastic material that is sometimes referred to as the organic matrix. The term matrix, which is widely used in descriptive anatomy, is derived from a Latin word meaning womb or uterus.
What is inorganic matrix bone made of?
What is inorganic matrix?
What are the components of an osteocyte?
The osteocytes are oval-shaped, multi-protuberant cells, and contain a single nucleus that is located toward the vascular side and has one or two nucleoli and a membrane.
What are osteocytes made of?
Osteocytes are derived from mesenchymal stem cells through osteoblast differentiation. Their entrapment within the bone matrix is possibly an active process and an embedment in neighbor osteoid forming osteoblasts (Bonewald, 2011).
What is an inorganic matrix?
Which is part of the inorganic matter that makes up the matrix of bone?
What is bone matrix made of?
Bone matrix The hardness and rigidity of bone is due to the presence of mineral salt in the osteoid matrix, which is a crystalline complex of calcium and phosphate (hydroxyapatite). Calcified bone contains about 25% organic matrix (2-5% of which are cells), 5% water and 70% inorganic mineral (hydroxyapatite).
Which of these is an inorganic component of the bone matrix quizlet?
The inorganic portion of the bone matrix is made up of salt crystals that are primarily calcium phosphate, Ca3(PO4)2. Calcium phosphate and calcium hydroxide interact to form crystals of hydroxyapatite, which is Ca10(PO4)6(OH)2.
Which of the following is an inorganic component of the bone matrix?