Can dengue cause strokes?
This study showed that patients with dengue had an increased risk of stroke, and this risk was time-dependent, as high as 2.49 times relative to control patients in the first 2 months. Patients with dengue who were male, who were older than 60 years or who had comorbidities had a higher incidence of stroke.
What is the etiology of dengue fever?
Dengue is a viral infection transmitted to humans through the bite of infected mosquitoes. The primary vectors that transmit the disease are Aedes aegypti mosquitoes and, to a lesser extent, Ae. albopictus. The virus responsible for causing dengue, is called dengue virus (DENV).
How does dengue affect the brain?
Headache, alteration of consciousness, irritability, insomnia, seizures and focal neurological deficit associated with encephalitis, encephalopathy and stroke pictures are the most common symptoms observed during the acute dengue.
How does dengue cause haemorrhage?
While the etiology of hemorrhage in patients with dengue is poorly understood, mild hemorrhagic manifestations might be due to increased capillary fragility as a result of thrombocytopenia or platelet dysfunction.
Can dengue cause neurological problems?
[24] Dengue fever can result in various neurological manifestations. Dengue infection should be considered and properly investigated in patients presenting with various neurological disorders without obvious etiology, especially if preceded by a febrile illness compatible with dengue fever.
How does dengue fever affect the circulatory system?
It is an unpleasant disease that can cause high fever, severe headache, and joint and muscle pain. But in some people, it can also cause small blood vessels to leak, which can lead to failure of the circulatory system, shock, and death.
What is shock syndrome in dengue?
Severe dengue haemorrhagic fever (previously dengue haemorrhagic fever and dengue shock syndrome) is characterised by severe plasma leakage, severe bleeding, and severe organ involvement manifested as elevated liver enzymes, impaired sensorium, and myocarditis.
What are the after effects of dengue fever?
Dengue leaves some long term ill effects including hair fall, alopecia, joint pain and muscle pain. As per a study which was published in April 2013 edition of Nature, around 390 million people are infected with dengue virus every year, globally.
Can dengue infect the brain?
Nowadays, an increasing number of dengue cases present damage in organs such as brain, liver, heart, or kidneys, an interesting and important feature that has been reported in some cases, but that has been very difficult to relate with the virus given the late onset of these complications.
Does dengue cause thrombosis?
We report five cases of large vein thrombotic events associated with the acute phase of dengue fever, including a previously non-reported case of mesenteric vein thrombosis. Complications such as these could have been overlooked in the diagnosis of dengue fever, given that the major concern is the hemorrhagic event.
Can dengue cause seizures?
The main symptoms of dengue encephalitis are headache, seizures and altered consciousness[8]. Typical symptoms of dengue fever like myalgias, rash and bleeding are seen in less than 50% of encephalitis cases[6].
Does dengue cause paralysis?
Patients with dengue fever can develop acute flaccid paralysis as a complication. In regions where dengue is hyperendemic, screening for dengue illness may be important in patients presenting with acute flaccid paralysis.
What are the main organs involved in dengue hemorrhagic fever?
The liver as a target of immune-mediated mechanisms in dengue fatal cases. The liver is considered as an important target for DENV infection and is the most common organ to be involved in the disease.
What is dengue hemorrhagic?
Dengue hemorrhagic fever (DHF): A syndrome due to the dengue virus that tends to affect children under 10, causing abdominal pain, hemorrhage (bleeding) and circulatory collapse (shock).
What causes hypotension in dengue?
Platelet counts below 100,000/mm3 together with a rise in the hematocrit define DHF. In the classical shock syndrome, increased vascular permeability results in third space fluid loss, leading to pleural effusions, pericardial effusions, ascites, non-cardiogenic pulmonary edema and, subsequently, hypotension.
Does dengue affect heart?
Dengue virus infection affects the heart structurally and functionally. Clinical manifestations of cardiac complications secondary to dengue virus infection vary from self-limiting arrhythmias to severe myocardial infarction, leading to hypotension, pulmonary edema, and cardiogenic shock.
Does dengue cross the blood brain barrier?
Using in vivo and in vitro models, researchers have demonstrated that DENV can affect the cells from the blood–brain barrier (BBB) in several ways, which could result in brain tissue damage, neuronal loss, glial activation, tissue inflammation and hemorrhages.
Why does thrombocytopenia occur in dengue?
The pathophysiology of thrombocytopenia in dengue infection is not clearly understood. It is believed that it rests mainly on two events: decreased in bone marrow production and/or increased peripheral destruction and clearance of platelets.
What are the symptoms of dengue hemorrhagic?
Symptoms include frontal headache, retro-orbital pain, myalgias, arthralgias, hemorrhagic manifestations, rash, and low white blood cell count. The patient also may complain of anorexia and nausea.
What is the number one cause of dengue?
Dengue. With more than one-third of the world’s population living in areas at risk for infection, dengue virus is a leading cause of illness and death in the tropics and subtropics. As many as 400 million people are infected yearly. Dengue is caused by any one of four related viruses transmitted by mosquitoes.
How is dengue spread?
Dengue viruses are spread to people through the bite of an infected Aedes species ( Ae. aegypti or Ae. albopictus) mosquito. Almost half of the world’s population, about 4 billion people, live in areas with a risk of dengue. Dengue is often a leading cause of illness in areas with risk. Dengue outbreaks are occurring in many countries of the world.
Should I be worried about dengue?
Protect yourself. Dengue viruses are spread to people through the bite of an infected Aedes species ( Ae. aegypti or Ae. albopictus) mosquito. Dengue is common in more than 100 countries around the world. Forty percent of the world’s population, about 3 billion people, live in areas with a risk of dengue.
Does dengue occur in the United States?
Although dengue rarely occurs in the continental United States, it is endemic in Puerto Rico and in many popular tourist destinations in Latin America, Southeast Asia and the Pacific islands.