What is Romazicon used for?
Flumazenil is used to reverse the effects of a benzodiazepine (BENZ-oh-dye-AYZ-e-peen) sedative such as Valium, Versed, Xanax, Tranxene, and others. Flumazenil is used to help you wake up after a surgery or medical procedure in which a benzodiazepine was used as a sedative.
How do you administer Romazicon IV?
To minimize the likelihood of pain or inflammation at the injection site, flumazenil should be administered through a freely flowing intravenous infusion into a large vein. Local irritation may occur following extravasation into perivascular tissues.
Can flumazenil be given IV?
Flumazenil is only approved for intravenous (IV) administration. The prescribed IV administration technique is to titrate slowly to arousal with 0.2 mg increments. It is supplied in a 0.1 mg/ml concentration only.
How fast does Romazicon work?
The onset of action is about 1 to 2 minutes; 80% response occurs within the first 3 minutes. The peak effect is 6 to 10 minutes after administration. The duration ranges from 19 minutes to 50 minutes, depending on the dose and benzodiazepine plasma concentrations.
What drugs does Romazicon reverse?
Romazicon (Flumazenil) is a benzodiazepine antogonist used to reverse Versed (Midazolam) and Valium (Diazepam). It also has a rapid onset of action, producing a reversal in less than one minute. A dose of 0.2 – 1 mg is given slowly intravenously with a dose not exceeding 0.2 mg/min.
How do I give Romazicon?
To minimize the likelihood of pain at the injection site, ROMAZICON should be administered through a freely running intravenous infusion into a large vein.
What is the reversal agent for midazolam?
Flumazenil in a dose of 0.15 mg is a safe drug that reverses the sedative effect of midazolam.
Where do you administer flumazenil?
What meds does Romazicon reverse?
Romazicon (Flumazenil) is a benzodiazepine antogonist used to reverse Versed (Midazolam) and Valium (Diazepam). It also has a rapid onset of action, producing a reversal in less than one minute.
What drug reverses general anesthesia?
Naloxone is very useful and specific for reversing adverse and life-threatening respiratory depression caused by narcotic drugs and should be used in these situations.
Can Romazicon cause seizures?
Flumazenil may cause seizures, especially in people who have sedative-addiction withdrawal symptoms or recent antidepressant overdose, people who have recently received injectable benzodiazepines, or people who had symptoms of a seizure just before receiving flumazenil.
How is Romazicon given?
How much Romazicon do you give?
For initial management of a known or suspected benzodiazepine overdose, the recommended initial dose of ROMAZICON is 0.2 mg (2 mL) administered intravenously over 30 seconds.
What is Romazicon used to reverse?
When do you administer flumazenil IV?
Usual Adult Dose for Reversal of Sedation Initial dose: 0.2 mg IV one time over 15 seconds. Repeated doses: 0.2 mg may be given every minute until the desired level of consciousness is achieved. Maximum total dose 1 mg.