Can neurofibromatosis cause brain tumors?
Conclusions. In summary, individuals with NF1 are predisposed to a variety of brain tumors such as optic pathway gliomas, brainstem gliomas, and glioblastomas that tend to act more indolently than their sporadic counterparts.
What are NF2 tumors?
Neurofibromatosis type 2 (NF2) is a genetic condition that causes tumours to grow along your nerves. The tumours are usually non-cancerous (benign) but may cause a range of symptoms. Neurofibromatosis type 1 (NF1) is covered separately because it has different symptoms and causes. It’s also much more common than NF2.
How rare is NF2?
NF2 is a rare disorder that affects males and females in equal numbers. All races and ethnic groups are equally affected by this disorder. The estimated incidence of NF2 is 1 in 33,000 people worldwide. The symptoms of this disease typically become apparent during puberty or early adulthood.
What’s the difference between NF1 and NF2?
The NF1 gene makes a protein called neurofibromin, which regulates cell division in the nervous system and functions as a kind of molecular brake to keep cells from growing out of control. The gene for NF2 is located on chromosome 22. The NF2 gene product is a tumor-suppressor protein (called merlin or schwannomin).
Where do NF2 tumors grow?
The main trait of NF2 is that noncancerous (benign) tumors grow on the nerves of the brain and the spine. In NF2, the auditory nerves, the ones that involve hearing, are commonly affected. Therefore, hearing is affected. These types of tumors grow along the auditory nerve that connects the brain and inner ear.
Is NF2 a disability?
Although neurofibromatosis is a serious condition, the Social Security Administration (SSA) does not specifically list the disorder as a disability. But, the symptoms that accompany the condition can be reviewed for benefits.
Does NF2 qualify for disability?
Does NF2 cause pain?
People who have NF2 may also develop other benign tumors. Signs and symptoms of these tumors can include: Numbness and weakness in the arms or legs. Pain.