What is the pathogenesis of dengue fever?
The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.
How can dengue be prevented?
Use insect repellent, wear long-sleeved shirts and long pants, and control mosquitoes inside and outside your home. Each year, an estimated 400 million people are infected with dengue virus through the bites of infected mosquitoes. About 100 million get sick.
What is transfused in dengue?
Prophylactic platelet transfusions are given in dengue fever with thrombocytopenia to prevent hemorrhagic complications. Although the use of prophylactic platelet transfusions is increasing in countries where dengue is endemic, it is associated with risks and has financial implications.
Which IV fluid is best for dengue?
An ideal intravenous fluid for patients with dengue is one that is isotonic. However, even isotonic crystalloid solutions have their limitations when used in large quantities.
What is dengue IgG IgM and NS1?
Dengue Antigen NS1, IgG and IgM test detects the non-structural protein component (NS1) of the dengue virus and the antibodies (IgG & IgM) produced by the body in response to the infection. NS1 and IgM is secreted into the blood during dengue infection and are detectable within 3-4 days of illness.
What is the best treatment of dengue fever?
Rest as much as possible. Take acetaminophen (also known as paracetamol outside of the United States) to control fever and relieve pain. Do not take aspirin or ibuprofen!
What is the critical platelet count in dengue?
A typical person has a platelet count of between 150,000 and 250,000 per microlitre of blood. About 80 to 90 per cent of patients with dengue will have levels below 100,000, while 10 to 20 per cent of patients will see critically low levels of 20,000 or less.
Where can I find the who guidelines for dengue treatment?
World Health Organization. (2009). Dengue guidelines for diagnosis, treatment, prevention and control : new edition. World Health Organization. https://apps.who.int/iris/handle/10665/44188
What are the prevention and response strategies for dengue?
The prevention of and response to dengue and other arboviruses involve developing and implementing preparedness plans. These should include early warning systems, epidemiological, entomological and environmental surveillance, laboratory support, clinical case management, vector control, environmental controls, risk communication
What are the six elements of dengue management?
consists of six elements: (i) dengue surveillance, (ii) case management, (iii) outbreak response, (iv) integrated vector management, (v) social mobilization and communication
What should the dengue programme include in its annual budget?
This will require that the dengue programme includes in its annual budget an allocation for social mobilization and communication activities in order to integrate these specialists into routine programme planning. Most ministries of health have health promotion or health education departments, and it is