What is BioPlex test?
The BioPlex 2200 fully-automated, random access, multiplex testing platform uses sets of coated magnetic beads as the basis for a range of autoimmune, infectious disease, and other immunoassays. Image.
What does syphilis IgG IgM mean?
USE OF TEST: The Syphilis Total IgG/IgM Multiplex Immunoassay (MIA) is a qualitative Immunoassay used for the detection of Treponema pallidum IgG and IgM antibodies in human sera. This assay is routinely performed as a screening test for all specimens ordered on the syphilis panel.
What is syphilis IgM?
IgM anti-treponemal antibody was found in virtually all cases of untreated early or early latent syphilis but in only 23 per cent. of sera from patients with untreated late latent syphilis.
Is RPR IgG or IgM?
The RPR detects non- treponemal antibodies (cardiolipin, cholesterol, and lecithin), whereas the new test detects IgG and IgM antibodies to T. pallidum proteins.
What BioPlex 2200?
The BioPlex 2200 System is a fully automated, random access multiplex testing platform that combines automation with the diagnostic power of proprietary multiplex chemistry and state-of-the-art eFlex software.
What is syphilis IgG antibody?
Treponemal assays (FTA, syphilis IgG) measure antibodies that directly react with the syphilis-causing organism T. pallidum, while non-treponemal assays (RPR, VDRL) measure antibodies against non-specific cardiolipin antigens released during treponemal infections.
How does the BioPlex 2200 work?
BioPlex 2200 immunoassays use magnetic 8 µm beads, infused with varying ratios of fluorescent dyes to create unique bead sets. Beads within each set are coated with a ligand (i.e., antigen, antibody, analyte, etc.) specific to a particular assay.
What is Ana blood test?
Overview. An ANA test detects antinuclear antibodies (ANA) in your blood. Your immune system normally makes antibodies to help you fight infection. In contrast, antinuclear antibodies often attack your body’s own tissues — specifically targeting each cell’s nucleus.