Which IV meds are vesicants?
IV Extravasation – Vesicant Medications
- Acyclovir > 7mg/mL (Zovirax®)
- Aminophylline.
- Calcium salts ( 100 mg/mL concentration)
- Chlorothiazide (Diuril®)
- Cisplatin (Platinol®)(in concentrations 0.5 mg/mL)
- Dactinomycin (Actinomycin-D, Cosmegen®)
- Daunorubicin (daunomycin, Cerubidine®)
- Dextrose solutions >10%
What are examples of vesicant IV solutions or medications?
Some common examples of vesicant medications and fluids include vancomycin, potassium chloride, calcium gluconate, dopamine, and Dilantin.
Which antibiotics are vesicants?
Vesicant antimicrobial defined as pH < 5 or > 9, or osmolality > 600 mosmol/L, including acyclovir, amikacin, ciprofloxacin, doxycycline, ganciclovir, gentamicin, levofloxacin, linezolid, trimethoprim-sulfamethoxazole, tobramycin, and vancomycin.
What IV drugs cause extravasation?
Examples of medications that can cause extravasation include: cytotoxic medications such as certain drugs used in chemotherapy; dyopamine; phenytoin (Dilantin); norepinephrine (Levophed) and phenylephrine (Neo-Synephrine).
Is IV contrast a vesicant agent?
A vesicant is an agent that has the potential to cause blistering or tissue necrosis. Radiologic contrast media are considered to be vesicant solutions.
Is Levophed a vesicant?
Examples of vasopressors include norepinephrine (Levophed), phenylephrine, (Neo-Synephrine), epinephrine, dopamine, dobutamine, and vasopressin. 2. Non-vesicants are IV solutions and medication that do not cause ischemia or necrosis.
Is vancomycin a vesicant?
Vancomycin is acidic (pH 2.5–4.0) and hyperosmolar (328 mOsm/L), which may make it a vesicant when administered through a peripheral line.
Is IV Lasix a vesicant?
Examples of non-vesicant solutions and medications include: Many antibiotics. Solumedrol (steroid) Ondansetron (Zofran) – anti-nausea drug. Furosemide (Lasix) – IV diuretic.
Is acyclovir IV A vesicant?
Acyclovir is a known vesicant medication administrated in paediatric patients, which appears to irritate venous and soft tissue if extravasated. However, only three patients with ex- travasation of IV acyclovir have been reported so far.
Is CT contrast dye a vesicant?
Is d10 a vesicant?
[Google Scholar] Dextrose is classified as a vesicant at concentrations of 10% or greater. The extravasation from the vein of hyperosmolar dextrose into the surrounding tissue leads to a large influx of fluid into the area.
Is propofol a vesicant drug?
Several case reports from 1961 through to 2014 have highlighted extravasation by thiopental or propofol [3]. It is well known that thiopental can act as a vesicant [7] and propofol can act as an irritant [8], [9], [10], [11]. However, few reports have shown the vesicant effects of propofol [12], [13], [14].
Is MRI contrast a vesicant?
Is D50 a vesicant?
Dextrose, at concentrations of 10% or greater, is also considered to be a vesicant, with rates of extravasation from 50% dextrose (D50) injections varying between 10–30% [2]. Case Report: A cachectic 48-year-old female with a past medical history of HIV, former IV drug use, and alcohol use, presented with lethargy.
Is dextrose a vesicant?
Is dobutamine a vesicant?
What is IV drug use, what drugs?
Intravenous, or IV drug use is the most common form of injection drug use. Users liquify and inject various drugs of abuse directly into their veins. The IV method requires certain tools called paraphernalia.
What are vesicant medications?
Acyclovir > 7mg/mL (Zovirax®)
What is vesicant chemotherapy?
Vesicant chemotherapy is a type of drug that is given during the chemotherapy process and that can cause blistering and swelling at the site of the injection. In extreme cases, a vesicant drug can go into nearby tissues, also known as extravasation, and can cause tissue or skin necrosis, or dead cells.
Is Zosyn a vesicant drug?
Zosyn contains a combination of piperacillin and tazobactam. Piperacillin and tazobactam are penicillin antibiotics that fight bacteria in the body. Zosyn is used to treat many different infections caused by bacteria, such as stomach infections, skin infections, pneumonia, and severe uterine infections.