What are HT1080 cells?
HT1080 (ATCC® CCL-121™) is a human fibrosarcoma cell line initiated from a 35-year-old Caucasian male. The cells are adherent with an epithelial morphology. Following implantation into immunocompromised mice, the cells form primary tumors and distant metastases.
Why are HEK293 cells used?
HEK 293 cells have been widely used in cell biology research for many years, because of their reliable growth and propensity for transfection. They are also used by the biotechnology industry to produce therapeutic proteins and viruses for gene therapy as well as safety testing for a vast array of chemicals.
Why are HaCaT cells used?
HaCaT cells are the immortalized human keratinocytes and have been extensively used to study the epidermal homeostasis and its pathophysiology. T helper cells play a role in various chronic dermatological conditions and they can affect skin barrier homeostasis.
Where do HaCaT cells come from?
HaCaT is a spontaneously transformed aneuploid immortal keratinocyte cell line from adult human skin, widely used in scientific research.
Is SW480 a ras proto oncogene?
This line has a mutation in codon 12 of the ras proto-oncogene, and can be used as a positive control for PCR assays of mutation in this codon. SW480 was established from a primary adenocarcinoma of the colon.
What is the pathophysiology of SW480?
SW480 was established from a primary adenocarcinoma of the colon. The stemline chromosome number is hypotriploid and 11-12 marker chromosomes were common. Both double minutes and dicentrics were observed in 8% of each metaphase examined.
What is the IC50 of erlotinib in SW480 cells?
Cytotoxic studies demonstrated that 85a and 85b possessed more inhibition potential towards SW480 cell line including IC50 values of 9.31 μM and 6.76 μM than that of standard drug erlotinib (IC 50 = 16.72 μM).
How do I get a certificate of origin for SW480 [sw-480] (ccl-228)?
To download a certificate of origin for SW480 [SW-480] ( CCL-228 ), enter the lot number exactly as it appears on your product label or packing slip. The certificate of origin for that lot of SW480 [SW-480] ( CCL-228) is not currently available online.