What is amifampridine used for?
Amifampridine is used to treat a certain disorder that affects nerves and muscles (Lambert-Eaton syndrome). This disorder causes your body’s immune system to attack healthy nerve cells, which results in muscle weakness.
Who manufactures firdapse?
The FIRDAPSE Pregnancy Registry: In conjunction with the FDA, Catalyst Pharmaceuticals has created a registry to collect information about the safety of FIRDAPSE use during pregnancy. Contact the registry as soon as you learn that you are pregnant by calling (855) 212-5856 or visiting www.firdapsepregnancystudy.com.
What class of drug is Amifampridine?
Amifampridine is a voltage gated potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome.
Is theophylline and aminophylline the same?
Aminophylline is a bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio.
When was firdapse approved?
Is FIRDAPSE approved for use elsewhere in the world? Yes. It was approved on December 28, 2009 for use in patients with Lambert-Eaton myasthenic syndrome in the European Union and is made available by the company BioMarin.
Which class of drug is aminophylline?
Aminophylline belongs to a group of medicines known as bronchodilators. Bronchodilators are medicines that relax the muscles in the bronchial tubes (air passages) of the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.
What is the other name for aminophylline?
Theophylline is available under the following different brand names: Theo 24, Theochron, Elixophyllin, aminophylline, and Uniphyl.
Is firdapse an orphan drug?
Because the number of patients with LEMS is low, the disease is considered ‘rare’, and Firdapse was designated an ‘orphan medicine’ (a medicine used in rare diseases) on 18 December 2002. The medicine can only be obtained with a prescription.
What is the other name of aminophylline?
What brand names are available for aminophylline? Norphyl, Phyllocontin, Truphylline.
What contains aminophylline?
Product(s) containing aminophylline:
- aminophylline systemic. Brand names: Phyllocontin, Truphylline.
- aminophylline/amobarbital/ephedrine systemic.
- aminophylline/ephedrine/guaifenesin/phenobarbital systemic.
- aminophylline/ephedrine/phenobarbital/potassium iodide systemic.
- aminophylline/guaifenesin systemic.
What drugs contain aminophylline?
Description and Brand Names
- Norphyl.
- Phyllocontin.
- Quibron-T.
What are the uses of amifampridine?
Amifampridine is used to treat Lambert-Eaton myasthenic syndrome in adults. Amifampridine may also be used for purposes not listed in this medication guide.
Is amifampridine phosphate an orphan drug?
Amifampridine phosphate has orphan drug status in the EU for Lambert–Eaton myasthenic syndrome and Catalyst holds both an orphan designation and a breakthrough therapy designation in the US.
What are the side effects of amifampridine?
The dose-limiting side effects include tingling or numbness, difficulty sleeping, fatigue, and loss of muscle strength. Amifampridine can cause seizures, especially but not exclusively when given at high doses and/or in particularly vulnerable individuals who have a history of seizures.