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What is a Transduodenal Ampullectomy?

What is a Transduodenal Ampullectomy?

Transduodenal surgical ampullectomy (TSA) is a limited surgical approach for pathologies of the duodenal major and minor papilla. The method was first described by Halsted in 1899.

What is endoscopic Ampullectomy?

Endoscopic ampullectomy is a minimally invasive method of treating superficial lesions of the ampulla of Vater. With careful patient selection and lesion assessment it is a safe and efficacious therapeutic procedure that can obviate the need for potentially major surgical intervention.

What is ampullary adenoma with high grade dysplasia?

Ampullary adenoma is a pre-cancerous lesion arising from the duodenal papilla that is often asymptomatic. It is important to distinguish whether the adenoma is sporadic or arises in the setting of familial adenomatous polyposis as this has important implications with respect to management and surveillance.

How is Ampullectomy performed?

The surgeon carefully identifies the pancreatic and bile ducts. Superficial cancerous cells on the ampulla are surgically removed (excised) with the help of needle-tip electrocautery. Both the pancreatic and bile ducts are marked with stitches before completing the excision.

What is a Ampullectomy?

An ampullectomy is a surgical procedure that is used to treat cancers of the hepatopancreatic duct (ampullary adenomas), small neuroendocrine tumors that develop in the ampulla of Vater and certain noncancerous conditions, such as inflammatory stenosis.

Can an ampullary tumor be benign?

Benign neoplasms of the ampulla of Vater are rare, representing less than 10 percent of periampullary neoplasms [1,2]. Adenomas are the most common benign lesions of the ampulla but have the potential to undergo malignant transformation to ampullary carcinomas [1,3-19].

What does Ampulla mean?

noun, plural am·pul·lae [am-puhl-ee, -pool-ee]. Anatomy. a dilated portion of a canal or duct, especially of the semicircular canals of the ear.

What is the function of the ampulla of Vater?

The cystic duct leaves the gallbladder and joins with the common hepatic duct to form the common bile duct. This duct subsequently joins with the pancreatic duct; this junction is known as the ampulla of Vater. The pancreatic duct delivers substances such as bicarbonate and digestive enzymes to the duodenum.

What causes ampullary carcinoma?

Experts aren’t sure what causes ampullary cancer. It occurs when cells in the body change and grow out of control. These abnormal cells may grow to form a lump or mass called a tumor. If they are in the body long enough, they can grow into (invade) nearby areas and spread to other parts of the body (metastasis).