What is the drug Venofer used for?
Venofer® (iron sucrose) injection, USP is an established and effective treatment for chronic kidney disease (CKD) patients experiencing iron deficiency anemia (IDA). Venofer provides IV iron therapy for the treatment of IDA in adult and pediatric patients 2 years and older with CKD.
When is Venofer given in pregnancy?
Iron deficiency anaemia occurring in the first trimester of pregnancy can in many cases be treated with oral iron. Treatment with Venofer should be confined to second and third trimester if the benefit is judged to outweigh the potential risk for both the mother and the foetus.
What is the side effect of Venofer?
Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Pain, swelling, or redness at the injection site may occur. If these effects continue or worsen, tell your doctor.
How long is Venofer good for?
Syringe Stability: Venofer, when diluted with 0.9% NaCl at concentrations ranging from 2 mg to 10 mg of elemental iron per mL, or undiluted (20 mg elemental iron per mL) and stored in a plastic syringe, was found to be physically and chemically stable for 7 days at controlled room temperature (25°C ± 2°C) and under …
When should a pregnant woman start taking iron?
An appropriate time to begin iron supplementation at a dose of 30 mg/day is after about week 12 of gestation (the beginning of the second trimester), when the iron requirements for pregnancy begin to increase.
Is 8 hemoglobin low during pregnancy?
According to the classification of World Health Organization (WHO), pregnant women with hemoglobin levels less than 11.0 g/dl in the first and third trimesters and less than 10.5 g/dl in the second trimester are considered anemic (Table I) (11).
How frequently can Venofer be given?
Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later.
Is Venofer safe?
Important Safety Information Venofer® may also increase the risk of low blood pressure. Tell your doctor right away if you experience unusual thirst, blurred vision, cold, clammy, and/or pale skin, lack of concentration, lightheadedness, and/or nausea. It may also increase the risk of iron overload (hemosiderosis).
How quickly does Venofer work?
Your doctor may order lab work during your treatment to determine if the treatment is working, or if you need additional treatment. It often takes 5 to 10 days after a Venofer® infusion to improve hemoglobin levels or feelings of fatigue.
How many Venofer infusions are needed?
Can too much iron harm a fetus?
Iron toxicity is mostly a problem for children, but the adult body will only utilize so much iron. The RDA for iron is 18 mg per day. If the pregnant woman consumes more than that in combination with her food and the prenatal vitamin, the body will simply not absorb that iron.
What is normal hemoglobin after delivery?
The mean predelivery and postpartum Hb levels were 12.3 (1.2) g/dl and 10.8 (1.4) g/dl, respectively. In our cohort, 15/58 women (25.9%) had a postpartum Hb<12 g/dl which meets criteria for postpartum anemia[21,22], and 1/58 (1.7%) women had a postpartum Hb<8 g/dl consistent with severe postpartum anemia[22].
What’s the normal Hb for a pregnant woman?
The normal physiologic range for hemoglobin during pregnancy is 11.5-13.0 (13.5) g/dl; anemia is, by definition, present when the values are under 11 g/dl and is quite common in pregnancy.
Who should not take Venofer?
Venofer® should not be used in patients who are younger than two years of age or those who have ever experienced an allergic reaction to an iron injection. Venofer® can also be passed to your baby through breast milk. Therefore, tell your doctor if you’re pregnant or breastfeeding so that you can discuss your options.
How fast does Venofer work?
It often takes 5 to 10 days after a Venofer® infusion to improve hemoglobin levels or feelings of fatigue. How many treatments will I need? Depending on the lab work results, you may need 1 to 4 Venofer® treatments. We usually schedule each treatment 5 to 14 days apart.
How long does Venofer last?
7-day Stability After Dilution. Venofer offers 7-day stability at controlled room temperature in both plastic syringes and IV admixtures diluted with 0.9% Sodium Chloride Injection (NaCl), avoiding potential waste.
¿Qué es el hierro sacarosa?
El hierro sacarosa, el principio activo de Venofer, se compone de un núcleo de hidróxido de hierro(III) polinuclear rodeado de una gran cantidad de moléculas de sacarosa enlazadas de forma no covalente. El complejo tiene una masa molecular promedio (Mw) de aproximadamente 43 kDa.
¿Qué es venofer y para qué se utiliza?
Qué es Venofer y para qué se utiliza Venofer es un medicamento que contiene hierro (en forma de hierro sacarosa). Los medicamentos que contienen hierro se utilizan cuando no se tiene hierro suficiente en el organismo.
¿Qué contiene la ampolla de hierro sacarosa?
Cada ampolla de 5ml contiene 20 mg/ml de hierro, como hierro sacarosa, correspondiente a 100 mg de hierro por ampolla. Forma farmacéutica: Solución inyectable o concentrado para solución para perfusión.
¿Qué es una sobredosis de hierro?
La sobredosis puede producir sobrecarga aguda de hierro, que puede manifestarse en forma de hemosiderosis. La sobredosis debería tratarse con medidas de sostenimiento y, cuando así se requiera, con un quelante del hierro. Ampollas de vidrio del tipo I con volumen extractable de 5 ml.