What is Sargramostim used for?
It is used to help your body make more white blood cells. White blood cells are important to help you fight off infections. Sargramostim is given to people whose ability to make white blood cells is reduced (for instance, due to chemotherapy or exposure to large amounts of radiation).
How do you administer leukine?
The recommended dose is 250 mcg/m²/day administered intravenously over a 2-hour period beginning two to four hours after bone marrow infusion, and not less than 24 hours after the last dose of chemotherapy or radiotherapy. Do not administer LEUKINE until the post marrow infusion ANC is less than 500 cells/mm³.
How do you reconstitute leukine?
Reconstitute LEUKINE for Injection aseptically with 1 mL of diluent. Do not mix the contents of vials reconstituted with different diluents together. Reconstitute with either Sterile Water for Injection, USP (without preservative) or Bacteriostatic Water for Injection, USP (0.9% benzyl alcohol).
What kind of drug is Sargramostim?
Sargramostin is in a class of medications called colony-stimulating factors. It works by helping the body make more neutrophils and certain other blood cells.
Is Sargramostim a biologic?
Drug type: Sargramostim is a biologic response modifier. It is classified as a colony stimulating factor (for more detail, see “How this drug works” section below).
What are the side effects of filgrastim?
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- Bleeding gums.
- bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site.
When should I take filgrastim injection?
Start using the medicine 24 hours or more after you finish your chemotherapy. However, do not use it within 24 hours before you begin another chemotherapy. Allow the medicine to warm to room temperature for 30 minutes before you inject it.
Is Leukine a chemotherapy drug?
What This Drug Is Used For: Used to accelerate the recovery of white blood cells following chemotherapy. Used following induction chemotherapy in Acute Myelogenous Leukemia (AML).
What is another name for Sargramostim?
Leukine is the trade name for sargramostim. GM-CSF is another name for sargramostim. In some cases, health care professionals may use the trade name leukine or other names GM-CSF when referring to the generic drug name sargramostim. Drug type: Sargramostim is a biologic response modifier.
What time of day should I take filgrastim?
How should I administer filgrastim? The injection should be given under the skin (subcutaneously) once a day, at about the same time each day: 1) To minimise any discomfort, leave the syringe you are intending to use for that day out of the fridge for 30 minutes before injecting. 2) Wash and dry your hands thoroughly.
How often should filgrastim be given?
It is usually given once a day, but filgrastim injection products (Neupogen, Nivestym, Zarxio) may be given twice a day when it is used to treat severe chronic neutropenia. The length of your treatment depends on the condition that you have and how well your body responds to the medication.
What is another name for sargramostim?
Is Leukine FDA approved?
On March 29, 2018, the FDA approved use of Leukine (sargramostim) to increase survival in adult and pediatric patients acutely exposed to myelosuppressive doses of radiation (Hematopoietic Syndrome of Acute Radiation Syndrome, or H-ARS). Myelosuppression occurs when radiation damages the bone marrow.
What time should filgrastim be given?
When should I administer filgrastim? The first filgrastim injection is usually given on the fourth day of your chemotherapy cycle for a total of seven days. Some chemotherapy treatments might require you to administer the filgrastim syringes on a different day.
Who makes leukine?
In 2018, Partner Therapeutics, Inc. (PTx) acquired the global rights to develop, manufacture, and commercialize Leukine ® (sargramostim) from Sanofi.
What is the generic name for Leukine?
Leukine (sargramostim) is a granulocyte-macrophage colony-stimulating factor (GM-CSF). It works like the naturally occurring G-CSF protein in your body to stimulate bone marrow to make neutrophils, a type of white blood cell that helps your body fight infections.