What are the quality control test for capsules?
Finished product quality control tests for capsule drug products
- a. Permeability and sealing.
- b. Potency and impurity content.
- c. Weight variation test.
- f. Uniformity of content.
- g. Disintegration time test for capsules.
- h. Dissolution test for capsules.
- i. Moisture content.
- j. Moisture permeation test.
What is quality control test in pharmacy?
Quality control (QC) testing of pharmaceuticals must be rigorous and involves multiple techniques including GC/MS, LC/MS, and elemental analysis techniques. Impurities can take many forms, from solids to volatiles and everything in between.
What is QA and QC in pharmaceutical industry?
Quality Assurance and Quality Control (QA, QC) is the various process management procedures employed to preserve and enhance the quality of products or services.
What is Pharmacopeial official quality control test of tablets?
Pharmacopoeial or Official tests. They are called official tests because the test methods are described in official compendia such as the British Pharmacopoeia, American Pharmacopoeias etc. They are standardized test procedures which have clearly stated limits under which compressed tablets could be accepted.
What is minimum gram factor?
The minim per gram factor is calculated by dividing the weight of base plus the gram of solid(BA+S) by the weight of mixture(W) per cubic centimeter or 16.23 minims (V). The lower the base adsorption of the solid and the higher the density of the mixture, the smaller the capsule will be.
What is quality control testing?
QC testing is a function of software quality that checks that the project follows standards, processes, and procedures laid down, and that the project produces the required internal and external deliverables. The QC team’s job is to identify defects after a product is developed but before it is released.
What is quality control in laboratory PDF?
Quality Control. –The process of detecting errors. The process of detecting errors. •Errors can occur even in the best of laboratories. Errors can occur even in the best of laboratories.
What is thickness test for tablets?
Tablet thickness is measured with a vernier caliper, thickness gauge or automated equipment (Automatic weight, hardness, thickness, and tablet diameter test instrument). The thickness of a tablet should be controlled within ±5% variation of a standard value depending on the size of the tablet.
What is ideal hardness of tablet?
Although there is not definite number for the hardness of the tablet, there is a recommended range which is most likely sufficient for handling, this is between 1.5-4 MPa or approx 15-40 Newton.
What is the bloom strength for capsules?
200-250 g
The Bloom strength: The gelatin used in hard capsule manufacture is of a higher bloom strength (200-250 g) than that used for soft capsules (150 g) because a more rigid film is required for the manufacturing process.
What is QC analysis?
Analytical quality control, commonly shortened to AQC, refers to all those processes and procedures designed to ensure that the results of laboratory analysis are consistent, comparable, accurate and within specified limits of precision.