Which drugs can cause meningitis?
Four groups of drugs have been associated with drug-induced aseptic meningitis (DIAM) (Table 1): nonsteroidal anti-inflammatory drugs (NSAIDs),1-42 antibiotics,43-73 intravenous immunoglobulins (IVIGs),74-99 and OKT3 monoclonal antibodies (directed against the T3 receptor and, therefore, pan T-cell antibodies).
Can chemicals cause meningitis?
However, meningitis can also develop due to other, non-infectious reasons, which include certain chemicals and cancers.
What is drug induced aseptic meningitis?
Drug-induced aseptic meningitis is a diagnosis of exclusion that is made after infectious causes have been ruled out. A temporal relationship between the use of the drug and subsequent onset of meningeal symptoms, negative CSF culture, and resolution of symptoms after drug withdrawal allow for a presumptive diagnosis.
What are the symptoms of chemical meningitis?
Bacterial and chemical meningitis can share the same clinical presentation, with headache, neck stiffness, fever, nausea/vomiting and altered general status.
How common is drug induced meningitis?
Epidemiology. The occurrence of aseptic meningitis in general is approximately 20 per 100,000, but the most common cause of aseptic meningitis is viral.
How common is drug induced aseptic meningitis?
Drug induced aseptic meningitis is a rare but challenging diagnosis, most commonly reported with nonsteroidal anti-inflammatory drugs and antibiotics. Trimethoprim/sulfamethoxazole is a sulfonamide that is widely used in clinical practice for the treatment and prophylaxis of various infections.
How do you get meningitis B?
People spread meningococcal bacteria to other people by sharing respiratory and throat secretions (saliva or spit). Generally, it takes close (for example, coughing or kissing) or lengthy contact to spread these bacteria. Fortunately, they are not as contagious as germs that cause the common cold or the flu.
What is the deadliest type of meningitis?
Bacterial meningitis, the most serious form of meningitis, can also be contagious, especially if it’s meningococcal meningitis. It’s spread through extended contact with an infected person.
How serious is chemical meningitis?
Without treatment, bacterial meningitis can cause severe brain damage and is potentially life-threatening. The bacteria that cause meningitis can enter the bloodstream and also cause septicaemia (blood poisoning).
What drugs can cause non infectious meningitis?
Drugs that can cause noninfectious meningitis include nonsteroidal anti-inflammatory drugs (NSAIDs) and certain antibiotics. Noninfectious meningitis due to NSAIDs may occur in people who have autoimmune disorders such as rheumatoid arthritis or systemic lupus erythematosus (lupus).
Is aseptic meningitis fatal?
Aseptic (viral) meningitis is serious but rarely fatal in healthy people with normal immune systems. Usually, symptoms last from 7 to 10 days and the patient recovers completely. People with this condition may have the following symptoms: Headache.
How does ibuprofen cause aseptic meningitis?
The higher incidence of ibuprofen-induced aseptic meningitis in patients with autoimmune disorders could be explained by the widespread use of NSAIDs or by their tendency to autoreact. The signs and symptoms of NSAID-induced meningitis may become evident a few minutes to several hours after intake of NSAIDS.
What can happen if you get meningitis B?
The bacteria that cause meningitis B can also cause septicemia, a bloodstream infection also known as blood poisoning. When not treated swiftly, meningitis B can cause serious complications, including deafness, the need for amputation, and death. Some people experience severe side effects or death even when treated.
Is chemical meningitis serious?
How long does it take to recover from chemical meningitis?
The average duration of hospitalization was 28.7 days for patients with bacterial meningitis, 11.5 days for patients with chemical meningitis, and 17.8 days for patients with IC meningitis.
How long can aseptic meningitis last?
Can too much ibuprofen cause meningitis?
Ibuprofen is a common nonsteroidal antiinflammatory drug that is the most frequent cause of aseptic meningitis induced by drugs. The incidence of this type of aseptic meningitis is increasing, mainly among patients with underlying autoimmune connective tissue disorder, but also among healthy people.
Can painkillers cause meningitis?
Non-steroidal anti-inflammatory drug (NSAID)-induced meningitis is a rare entity that presents with acute or recurrent symptoms and signs of aseptic meningitis.