What is the function of the spleen?
The spleen participates in the creation of blood cells and also helps to filter out the blood, removing old blood cells and fighting infection.
What is the function of Ctf4?
Ctf4 was originally identified as a DNA polymerase α-interacting factor, important for chromosome stability. It was subsequently shown to be important for sister chromatid cohesion (Hanna et al., 2001, Kouprina et al., 1992, Miles and Formosa, 1992).
What are the types of tissue in the spleen?
The types of tissue in the spleen are: White pulp: As part of the immune system, the white pulp produces white blood cells. These blood cells make antibodies.
How do Ctf4 and CHL1 achieve chromosome stability?
However, the molecular mechanism by which Ctf4 and Chl1 achieve this is not known. Ctf4 was originally identified as a DNA polymerase α-interacting factor, important for chromosome stability. It was subsequently shown to be important for sister chromatid cohesion ( Hanna et al., 2001, Kouprina et al., 1992, Miles and Formosa, 1992 ).
How does the spleen stimulate the activation of lymphocytes?
This means that the spleen filters blood and presents foreign particles (antigens) to the lymphocytes it houses. In this way, the spleen stimulates the maturation and activation of lymphocytes. By filtering blood, the spleen also recycles senescent and damaged erythrocytes.
How does the spleen affect the red blood cells?
It affects the number of red blood cells that carry oxygen throughout your body, and the number of platelets, which are cells that help your blood to clot. It does this by breaking down and removing cells that are abnormal, old, or damaged. The spleen also stores red blood cells, platelets, and infection-fighting white blood cells.
How does the spleen store iron?
Always economical, your spleen saves any useful components from the old cells, such as iron. It stores iron in the form of ferritin or bilirubin, and eventually returns the iron to your bone marrow, where hemoglobin is made.